Cajun Chicken Alfredo
216 CommentsUpdated Jan 28, 2026
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Creamy cajun chicken fettuccine alfredo is a perfect meal for any weeknight. You can make a homemade Cajun alfredo sauce and tender chicken in the slow cooker, then add cooked fettuccine noodles to complete the dish.
Featured Comment
This was absolutely perfect ❤️ I made it for the first time yesterday ! My son is raving over it. We are just two so want to have it again tonight.
- pam
Cajun chicken pasta is a great spicy recipe for pasta night! This pasta has a bit of a kick to it, mainly from the cayenne. It was a nice change from my regular pasta recipes. My recipe is from scratch - no jarred Alfredo. Has just the right amount of heat and creaminess. The slow cooker makes great southern meals, also try my new recipe for Swamp Potatoes.
Key Ingredients
- Chicken - Use boneless skinless chicken breasts for this dish. They shred up perfectly.
- Seasonings - Make a homemade cajun seasoning blend with cayenne pepper, red pepper flakes, oregano, onion powder, garlic powder, paprika, salt, and pepper. You can add more cayenne pepper for a bolder cajun flavor.
- Chicken broth - This is the base of the sauce and will help keep chicken breast moist during the cooking process.
- Heavy Cream - Makes the dish creamy and helps thicken it, don't use half and half or milk.
- Parmesan Cheese - This adds flavor to the creamy alfredo sauce. You can use shredded parmesan cheese or grated parmesan cheese.
- Fettuccine Noodles - A classic noodle for cajun chicken pasta.
How to Make Cajun Chicken Alfredo
- Cook the chicken in seasoned broth until tender.
- Shred the chicken, then stir in cream, parmesan, and cooked pasta.
- Let it warm through until the sauce thickens and everything is well combined.
Tips & Variations
Shrimp - Add shrimp 15 minutes before the cooking time is done. Shred the chicken, add the cream and noodles and cook for the 20 additional minutes still. Make sure the shrimp is cooked through.
Andouille sausage - You can add one pound of sliced andouille sausage at the beginning of the cooking time.
Pasta Swap - You can use penne pasta instead of fettuccine noodles for a heartier noodle.
Add Veggies: To make this a complete meal, add steamed broccoli or frozen peas to the pasta just before serving.
Cream Swap: You can add a block of cream cheese to this dish instead of heavy cream. You can add it at the beginning of the cooking time, or microwave it for 30 seconds before adding the dish at the end of the cooking time.
Cajun Seasoning: You can use two teaspoons of cajun spice seasoning (such as Tony's Chachere's Creole Seasoning) instead of the different seasonings in this dish. Don't add any more, for it can be on the salty side.
Why isn't my Pasta Spicy?
Cayenne pepper loses its potency the longer it's been on the shelf, or it may not be as spicy as other brands. You can add additional cayenne pepper after the dish is done cooking for more Cajun spice.
How to Video
Ingredients
- 1 cup chicken broth
- 1/4 tsp. cayenne pepper
- 1/2 tsp. garlic powder
- 1/4 tsp. onion powder
- 1/2 tsp. dried leaf oregano
- 1/4 tsp. red pepper flakes
- 1 1/2 tsp. paprika
- 1 tsp. salt
- 1/4 tsp. pepper
- 2 lbs. boneless skinless chicken breasts
- 1 small white onion, diced
Add at the end:
- 1 lb. fettuccine noodles, cooked according to package directions
- 2 cups heavy cream
- 3/4 cup parmesan cheese, divided
- dried parsley or oregano for garnish
- paprika for garnish
Instructions
- Add the chicken broth to the slow cooker, add the cayenne, garlic powder, onion powder, oregano, red pepper flakes, paprika, salt and pepper. Stir.
- Add the chicken breasts and flip them around in the seasoned chicken broth to get the seasonings on the chicken.
- Sprinkle the onions over the chicken and broth.
- Cover and cook on low for 6 hours without opening the lid during the cooking time.
- After the cooking time is done, shred the chicken with two forks right in the slow cooker. Add the heavy cream.
- Add the cooked and drained pasta and a ½ cup of the Parmesan cheese. Stir.
- Sprinkle over the remaining parmesan cheese. I added a touch more paprika and also parsley flakes to the top of my pasta to make it look pretty. Cover and cook for 20 more minutes. Cooking for a bit longer helps the sauce thicken from the gluten in the pasta.
- Serve and enjoy!
Nutrition
Nutrition info is auto-generated. This information is an estimate; if you are on a special diet, please use your own calculations.
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Thanks!!! I dont know if there is a difference, but it is all I can ever find when a recipe calls for it. Trying this tomorrow!!
Can I use heavy whipping cream instead?
Yes! that’s what I often find and use.
Do you think you could freeze this meal ahead of time and then throw everything into the crockpot with the exception of the noodles?
I’d wait on the cream and cheese, but yes you could do the other ingredients.
How can you make the sauce thicker and no so thin and runny?
Did you make it? Add more cheese maybe, mine thickened up after the pasta sat with the sauce for a bit.
This sounds delicious and I cannot wait to try making this recipe for an upcoming date night. I do have a question for you on cooking time. By the time I would set my crockpot on to the time I would arrive home from work, it would be 10 hours. Any recommendations? Would it ruin the dish if I cooked it on low for 10 hours? Sorry, I’m very new to cooking and am not sure how crockpots work.
I think 8 hours would be the longest I would try cooking this for, sorry!
If I lower this to 2-3 people I would just half the ingredients right? New to cooking so making sure
It’s hard to tell without testing it. I apologize.
Hey stupid question I am new into the cooking game. If I want to down size this for 2-3 people would I just half all the ingredients listed right? Thanks for any advice I am excited to try this tomorrow or monday!
Do you fully cook the fettuccine, and then put it in the slow cooker for another 20 MINUTES? Won’t that overcook the pasta?
No, the slow cooker heats very slowly and the heavy cream that was added cooled down the sauce.
If I’m using gluten free noodles would it not need to be cooked 20 additional minutes?
possibly not. I know egg noodles would fall apart in that extra 20 mins, so possible the gluten free would do the same.
What kind of parmesan. Cheese! Grated (like speghett] or shredded
I used the grated (the finer kind)