Cajun Chicken Alfredo
216 CommentsUpdated Jan 28, 2026
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Creamy cajun chicken fettuccine alfredo is a perfect meal for any weeknight. You can make a homemade Cajun alfredo sauce and tender chicken in the slow cooker, then add cooked fettuccine noodles to complete the dish.
Featured Comment
This was absolutely perfect ❤️ I made it for the first time yesterday ! My son is raving over it. We are just two so want to have it again tonight.
- pam
Cajun chicken pasta is a great spicy recipe for pasta night! This pasta has a bit of a kick to it, mainly from the cayenne. It was a nice change from my regular pasta recipes. My recipe is from scratch - no jarred Alfredo. Has just the right amount of heat and creaminess. The slow cooker makes great southern meals, also try my new recipe for Swamp Potatoes.
Key Ingredients
- Chicken - Use boneless skinless chicken breasts for this dish. They shred up perfectly.
- Seasonings - Make a homemade cajun seasoning blend with cayenne pepper, red pepper flakes, oregano, onion powder, garlic powder, paprika, salt, and pepper. You can add more cayenne pepper for a bolder cajun flavor.
- Chicken broth - This is the base of the sauce and will help keep chicken breast moist during the cooking process.
- Heavy Cream - Makes the dish creamy and helps thicken it, don't use half and half or milk.
- Parmesan Cheese - This adds flavor to the creamy alfredo sauce. You can use shredded parmesan cheese or grated parmesan cheese.
- Fettuccine Noodles - A classic noodle for cajun chicken pasta.
How to Make Cajun Chicken Alfredo
- Cook the chicken in seasoned broth until tender.
- Shred the chicken, then stir in cream, parmesan, and cooked pasta.
- Let it warm through until the sauce thickens and everything is well combined.
Tips & Variations
Shrimp - Add shrimp 15 minutes before the cooking time is done. Shred the chicken, add the cream and noodles and cook for the 20 additional minutes still. Make sure the shrimp is cooked through.
Andouille sausage - You can add one pound of sliced andouille sausage at the beginning of the cooking time.
Pasta Swap - You can use penne pasta instead of fettuccine noodles for a heartier noodle.
Add Veggies: To make this a complete meal, add steamed broccoli or frozen peas to the pasta just before serving.
Cream Swap: You can add a block of cream cheese to this dish instead of heavy cream. You can add it at the beginning of the cooking time, or microwave it for 30 seconds before adding the dish at the end of the cooking time.
Cajun Seasoning: You can use two teaspoons of cajun spice seasoning (such as Tony's Chachere's Creole Seasoning) instead of the different seasonings in this dish. Don't add any more, for it can be on the salty side.
Why isn't my Pasta Spicy?
Cayenne pepper loses its potency the longer it's been on the shelf, or it may not be as spicy as other brands. You can add additional cayenne pepper after the dish is done cooking for more Cajun spice.
How to Video
Ingredients
- 1 cup chicken broth
- 1/4 tsp. cayenne pepper
- 1/2 tsp. garlic powder
- 1/4 tsp. onion powder
- 1/2 tsp. dried leaf oregano
- 1/4 tsp. red pepper flakes
- 1 1/2 tsp. paprika
- 1 tsp. salt
- 1/4 tsp. pepper
- 2 lbs. boneless skinless chicken breasts
- 1 small white onion, diced
Add at the end:
- 1 lb. fettuccine noodles, cooked according to package directions
- 2 cups heavy cream
- 3/4 cup parmesan cheese, divided
- dried parsley or oregano for garnish
- paprika for garnish
Instructions
- Add the chicken broth to the slow cooker, add the cayenne, garlic powder, onion powder, oregano, red pepper flakes, paprika, salt and pepper. Stir.
- Add the chicken breasts and flip them around in the seasoned chicken broth to get the seasonings on the chicken.
- Sprinkle the onions over the chicken and broth.
- Cover and cook on low for 6 hours without opening the lid during the cooking time.
- After the cooking time is done, shred the chicken with two forks right in the slow cooker. Add the heavy cream.
- Add the cooked and drained pasta and a ½ cup of the Parmesan cheese. Stir.
- Sprinkle over the remaining parmesan cheese. I added a touch more paprika and also parsley flakes to the top of my pasta to make it look pretty. Cover and cook for 20 more minutes. Cooking for a bit longer helps the sauce thicken from the gluten in the pasta.
- Serve and enjoy!
Nutrition
Nutrition info is auto-generated. This information is an estimate; if you are on a special diet, please use your own calculations.
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I’ve made this a few times and it’s very good. I actually add a little more spice since my family likes more. I also feel the cream dilutes it a bit. My issue is it never gets thick enough.
This is the same for me. I just can’t get it to thicken :/
It was great!
Can you use chicken stock instead of chicken broth?
Yes!
If I were to use gluten free pasta how can I still get it to thicken at the end ?
This recipe is delicious! We have it for dinner every couple of weeks. I find it is seasoned perfectly according to the recipe. Thank you for sharing!
Do you think it would be okay to use half n half instead of heavy cream. Its told me either or on a different recipe and its all I have
I will be thinner, but would work fine.
My husband loves this meal. We just add some cooked peas to it in the end and really like it.
Peas are such a great idea! My family loves peas.
I made this last night and it turned out great. I did add a can of Rotel’s roasted tomatoes like someone had commented. I used frozen chicken breasts instead. I cooked it on high for 3 hrs, but 2.5 hrs should be good enough. Just check the temp with a meat thermometer. The only thing I’d do different is add less whipping cream. Maybe 1 cup instead of 2. Took forever to thicken and was kind of soupy. You can also add mushrooms and spinach at the end with the cream.
Thanks for the tips, sounds great with the mushrooms and spinach.
I made this for dinner last night. My husband absolutely loved it. I myself like a little more flavor in the dish and thought it could use a bit more spice. Overall it’s a good dish and we will definitely be making it again.
What kind of heavy cream did you use?
I’m unsure, I usually use the store brand.