Chicken Biscuit Casserole


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Putting together a quick and easy comfort food that’s made in one pot has never been easier than with this Slow Cooker Chicken Biscuit Casserole. This meal idea is perfect for getting rid of leftover chicken and calls for other simple ingredients such as biscuits, frozen vegetables, and shredded cheddar cheese.

If you’re looking for more recipes that call for biscuits, try my Crockpot Chicken and Dumplings Recipe or Easy Slow Cooker Chicken Pot Pie (with biscuits).

Chicken casserole with biscuits in the crockpot.
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The prep time with this chicken and biscuits is super short because you can use store bought rotisserie chicken or chicken from a previously cooked meal. You also don’t have to worry about making anything from scratch as you’ll use refrigerated biscuits, cream of chicken soup in the can, frozen mixed vegetables, and traditional seasonings. I like to call this dish chicken bubble up casserole!

Key Ingredients

Here is all you need for this easy chicken biscuit dinner. Find the full recipe in the recipe card below the images.

Ingredients for chicken bubble up casserole on a table.
  • Rotisserie Chicken: This type of shredded chicken is known as a healthier choice of chicken because of the way it’s cooked. It’s also tastier because of the seasonings often used when cooking it.
  • Biscuits: Skip making homemade biscuits and use the biscuit dough in the can. You’ll cut them into cubes for easier cooking and mixing into the chicken mixture.
  • Frozen Vegetables: Like a pot pie, this recipe uses a vegetable medley of frozen peas, corn, carrots, and green beans.
  • Shredded Cheese: Cheddar cheese makes any casserole dish better.
  • Creamy Sauce Mixture: Milk and cream of chicken soup help create the creamy sauce base that the chicken, biscuits, and vegetables slow cook in.
  • Seasonings: Black pepper, onion powder, garlic powder, and chili powder combine to create an irresistible flavor.

How to Make Chicken and Biscuit Casserole

Follow my easy steps to make this chicken dinner in your Crock Pot.

Four images showing how to make chicken bubble up casserole in a crock pot.

Step One – In a large bowl, mix together the chicken, cream of chicken soup, milk, seasonings, frozen vegetables, and half the shredded cheese until everything is well blended.

Step Two – Add in the biscuit pieces (cut each into 6 chunks) and gently fold them into the mixture, making sure they’re fully coated.

Step Three – Lightly grease your slow cooker with cooking spray, then pour in the mixture and spread it evenly. Sprinkle the rest of the cheese over the top.

Step Four – Cover and cook on LOW for 3.5 to 4 hours, or until the biscuits are fully cooked through. Scoop and serve!

close up of chicken bubble up casserole with wooden spoon in it.

Quick Tip

This Chicken and Biscuit Casserole has a texture more like chicken and dumplings, not crisp oven-baked biscuits. It’s a cozy, comforting meal that’s full of flavor and perfect for a family dinner.

plate of chicken bubble up casserole
close up of chicken bubble up casserole with wooden spoon in it.

Chicken and Biscuit Casserole Recipe

5 from 1 vote
Prep Time: 20 minutes
Cook Time: 3 hours 5 minutes
Total Time: 3 hours 25 minutes
Servings: 6
Chicken and Biscuits Casserole is a creamy, comforting slow cooker meal made with tender chicken, veggies, and fluffy biscuit pieces all cooked together.

Ingredients 
 

  • 1 rotisserie chicken, meat picked off the bones and cubed (about 3 cups)
  • 1 cup milk
  • 21 oz. cream of chicken soup
  • 1 tsp. onion powder
  • 1 tsp. garlic powder
  • 2 tsp. chili powder
  • ½ tsp. ground black pepper
  • 2 cups shredded sharp cheese, divided
  • 2 cups frozen mixed vegetables, from a 10-16 oz. bag
  • 16.3 oz. can refrigerated biscuit dough, Pillsury works best

Instructions 

  • Spray the oval slow cooker with nonstick spray. In a large bowl stir together the chicken, cream of chicken soup, milk, seasonings, 1/2 the cheese and all the frozen mixed vegetables. Cut each biscuit into 6 pieces each. Stir the biscuits into the soup mixture.
  • Pour that mixture into the slow cooker and sprinkle with the remaining cheese.
  • Cook on low for 3.5-4 hours or until the biscuits are set in the middle.
  • Serve and enjoy!

Sarah’s Notes

  • Want to cook in the oven? Follow the directions for mixing and pour everything into a prepared baking dish. Place the baking dish into a preheated oven (no more than 375 degrees) and cook for 35-45 minutes uncovered until the biscuits are no longer doughy.
  • Extra cheese, a dollop of sour cream, chopped bacon, and chopped green onions make perfect toppings.
  • Add any remaining casserole into an airtight container and keep them in the fridge for up to 3 days. Reheat over medium heat to medium high heat.

Nutrition

Calories: 776kcal | Carbohydrates: 57g | Protein: 47g | Fat: 41g | Saturated Fat: 14g | Polyunsaturated Fat: 7g | Monounsaturated Fat: 10g | Cholesterol: 147mg | Sodium: 2071mg | Potassium: 464mg | Fiber: 4g | Sugar: 5g | Vitamin A: 3905IU | Vitamin C: 7mg | Calcium: 388mg | Iron: 4mg

Nutrition info is auto-generated. This information is an estimate; if you are on a special diet, please use your own calculations.

Made this recipe? Leave a comment below!

More Slow Cooker Chicken Recipes

Jalapeño Popper Chicken Chili and Chicken Broccoli Stuffing Casserole are both hearty, comfort food favorites—one with a spicy, cheesy kick and the other with a classic savory combo.

Lemon Chicken and Rice Soup and Chicken à la King offer two cozy options—one light and citrusy, the other creamy and rich with tender vegetables.

Mississippi Chicken and Slow Cooker Chicken Tortilla Soup bring bold flavors to the table, with zesty seasonings and juicy shredded chicken in every bite.

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Recipe Rating




10 Comments

  1. Jessica says:

    Could this be cooked on low over a longer period of time?

    1. Sarah Olson says:

      I don’t think it could go much longer, maybe 5 hours at the most. Might burn on the edges.

  2. June Uss says:

    can you use ground beef instead of chicken and then just replace the chicken soup with mushroom soup?

    1. Sarah Olson says:

      I don’t see why not, I would brown the beef first.

  3. Lisa H says:

    5 stars
    This receipe is quick, easy and cooks up in no time.
    I use my crockpot all the time and I am very happy I discovered the magicalslowcooker..
    I tried your receipe for new years, black eyed peas and it was a winner! Never cooked black eyed peas before and it turned out amazing..
    Thanks !!

  4. Patt says:

    Have you made this with uncooked fresh chicken?

    1. Sarah Olson says:

      I have not tested with uncooked chicken, it may work though with a little more cooking time.

  5. Anthony smith says:

    Living in England I have heard of biscuits but never actually seen them to buy, are they like dumplings. The recipe sounds lovely & I would love to try it out

  6. Tim says:

    Do you have any recipes with under 1000mg of sodium. Your recipeโ€™s look delicious but very high in fats and sodium.

    1. Sarah Olson says:

      I do, if you are on a low sodium diet you can change ingredients to make them lower as well.