Cajun Chicken Alfredo
214 Comments Jun 23, 2022
Updated Aug 08, 2025
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Creamy cajun chicken fettuccine alfredo is a perfect meal for any weeknight. You can make a homemade Cajun alfredo sauce and tender chicken in the slow cooker, then add cooked fettuccine noodles to complete the dish.
Featured Comment
This was absolutely perfect ❤️ I made it for the first time yesterday ! My son is raving over it. We are just two so want to have it again tonight.
– pam
Cajun chicken pasta is a great spicy recipe for pasta night! This pasta has a bit of a kick to it, mainly from the cayenne. It was a nice change from my regular pasta recipes. My recipe is from scratch – no jarred Alfredo. Has just the right amount of heat and creaminess.
Key Ingredients
- Chicken – Use boneless skinless chicken breasts for this dish. They shred up perfectly.
- Seasonings – Make a homemade cajun seasoning blend with cayenne pepper, red pepper flakes, oregano, onion powder, garlic powder, paprika, salt, and pepper. You can add more cayenne pepper for a bolder cajun flavor.
- Chicken broth – This is the base of the sauce and will help keep chicken breast moist during the cooking process.
- Heavy Cream – Makes the dish creamy and helps thicken it, don’t use half and half or milk.
- Parmesan Cheese – This adds flavor to the creamy alfredo sauce. You can use shredded parmesan cheese or grated parmesan cheese.
- Fettuccine Noodles – A classic noodle for cajun chicken pasta.
How to Make Cajun Chicken Alfredo
- Cook the chicken in seasoned broth until tender.
- Shred the chicken, then stir in cream, parmesan, and cooked pasta.
- Let it warm through until the sauce thickens and everything is well combined.
Tips & Variations
Shrimp – Add shrimp 15 minutes before the cooking time is done. Shred the chicken, add the cream and noodles and cook for the 20 additional minutes still. Make sure the shrimp is cooked through.
Andouille sausage – You can add one pound of sliced andouille sausage at the beginning of the cooking time.
Pasta Swap – You can use penne pasta instead of fettuccine noodles for a heartier noodle.
Add Veggies: To make this a complete meal, add steamed broccoli or frozen peas to the pasta just before serving.
Cream Swap: You can add a block of cream cheese to this dish instead of heavy cream. You can add it at the beginning of the cooking time, or microwave it for 30 seconds before adding the dish at the end of the cooking time.
Cajun Seasoning: You can use two teaspoons of cajun spice seasoning (such as Tony’s Chachere’s Creole Seasoning) instead of the different seasonings in this dish. Don’t add any more, for it can be on the salty side.
Why isn’t my Pasta Spicy?
Cayenne pepper loses its potency the longer it’s been on the shelf, or it may not be as spicy as other brands. You can add additional cayenne pepper after the dish is done cooking for more Cajun spice.
Cajun Chicken Alfredo Recipe
How to Video
Ingredients
- 1 cup chicken broth
- 1/4 tsp. cayenne pepper
- 1/2 tsp. garlic powder
- 1/4 tsp. onion powder
- 1/2 tsp. dried leaf oregano
- 1/4 tsp. red pepper flakes
- 1 1/2 tsp. paprika
- 1 tsp. salt
- 1/4 tsp. pepper
- 2 lbs. boneless skinless chicken breasts
- 1 small white onion, diced
Add at the end:
- 1 lb. fettuccine noodles, cooked according to package directions
- 2 cups heavy cream
- 3/4 cup parmesan cheese, divided
- dried parsley or oregano for garnish
- paprika for garnish
Instructions
- Add the chicken broth to the slow cooker, add the cayenne, garlic powder, onion powder, oregano, red pepper flakes, paprika, salt and pepper. Stir.
- Add the chicken breasts and flip them around in the seasoned chicken broth to get the seasonings on the chicken.
- Sprinkle the onions over the chicken and broth.
- Cover and cook on low for 6 hours without opening the lid during the cooking time.
- After the cooking time is done, shred the chicken with two forks right in the slow cooker. Add the heavy cream.
- Add the cooked and drained pasta and a ½ cup of the Parmesan cheese. Stir.
- Sprinkle over the remaining parmesan cheese. I added a touch more paprika and also parsley flakes to the top of my pasta to make it look pretty. Cover and cook for 20 more minutes. Cooking for a bit longer helps the sauce thicken from the gluten in the pasta.
- Serve and enjoy!
Nutrition
Nutrition info is auto-generated. This information is an estimate; if you are on a special diet, please use your own calculations.
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We make this atleast 1x a week. I have very picky eaters at our home and this is my go to for them. We make it directly how thr recipe reads.
Can I use frozen chicken?
I recommend thawing all meats prior to slow cooking.
recipe was great but way too thick for me so added some pasta water & it was better
Very good, not heavy like an Alfredo. Just the right amount of spicy. .
I absolutely loved this!!! Wondering how to make it a little more saucy. There wasn’t much sauce in mine
I’m making this rn. But I’d suggest just add a bit more cream to it. Just kind of use your discretion, i always find the first time i make a recipe it’s good but sometimes not, that’s when you know what could’ve went wrong and just know for nxt time what ckuld be different.
Ps I always turn my slow cooker on to warm up. Then u can start prepping aa it heats up. Also I always sear my meats before adding to the slow cooker. Adds amazing flavours! Won’t be disappointed.
Hope this helped!
For those whose came out runny. Mine was a little runny. I’ll I did was put it in a large bowl, added more parmigiana reggiano and that solved the problem. Also for those who say it’s dry. I didn’t shred the chicken but cut it into chunks as it would eventually shred on its own. Came out great. Only thing I substituted was the cheese from Parmesan to parmigiana reggiano
BEST PASTA EVER! We make it all the time
How long would you cook it for on high? Thank you
3.5- 4 hours.
This dish was incredible! So delicious and easy to throw together. I used the Tony’s Creole seasoning and found it not as spicy as I would like, so I definitely will add a bit of Cayenne Pepper as you suggested next time! Thanks for this gem of a recipe!
Wondering how long the leftovers Last
About 3 days.