Slow Cooker Cajun Chicken Fettuccine Alfredo


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Creamy cajun chicken fettuccine alfredo is a perfect meal for any weeknight. You can make a homemade cajun alfredo sauce and tender chicken in the slow cooker, then add cooked fettuccine noodles to complete the dish.

If you are looking for a plain chicken alfredo recipe, try my crockpot chicken alfredo recipe.

Close up of cajun chicken fettuccine in slow cooker.

This slow cooker Cajun chicken fettuccine was one of those recipes that changed after the ingredients were bought. I had planned to make a dish called chicken lazone, but decided to add a few more Cajun seasonings, then add pasta and Parmesan cheese to the pot at the end of the cooking time, along with the cream.

Cajun chicken alfredo pasta is a great spicy recipe for pasta night! This pasta has a bit of a kick to it, mainly from the cayenne. It was a nice change from my regular pasta recipes.

Recipe Ingredients

Ingredients for cajun chicken fettuccine with text.
  • Chicken – Use boneless skinless chicken breasts for this dish. They shred up perfectly.
  • Seasonings – Make a homemade cajun seasoning blend with cayenne pepper, red pepper flakes, oregano, onion powder, garlic powder, paprika, salt, and pepper. You can add more cayenne pepper for a bolder cajun flavor.
  • Chicken broth – This is the base of the sauce and will help keep chicken breast moist during the cooking process.
  • Heavy Cream – Makes the dish creamy and helps thicken it, don’t use half and half or milk.
  • Parmesan Cheese – This adds flavor to the creamy alfredo sauce. You can use shredded parmesan cheese or grated parmesan cheese.
  • Fettuccine Noodles – A classic noodle for cajun chicken pasta.
How to add ingredients for cajun chicken and shred chicken in slow cooker.

Step One – Add the chicken broth to the slow cooker. Add the seasonings to the chicken broth and stir. Add the chicken breasts to the broth.

Step Two – Add the onion on top of the chicken.

Step Three – Cook on low for 6 hours.

Step Four – Shred the chicken with two forks right in the slow cooker.

How to add cream, noodles and parmesan to chicken in slow cooker.

Step Five – Add the heavy cream.

Step Six – Add the cooked and drained fettuccine noodles and a 1/2 cup of parmesan cheese.

Step Seven – Stir gently.

Step Eight – Add additional parmesan cheese, parmesan, paprika, and parsley (or oregano) on top—Cook for an additional 20 minutes. Serve the alfredo pasta with salad and bread sticks.

Variations

  • Shrimp – Add shrimp 15 minutes before the cooking time is done. Shred the chicken, add the cream and noodles and cook for the 20 additional minutes still. Make sure the shrimp is cooked through.
  • Andouille sausage – You can add one pound of sliced andouille sausage at the beginning of the cooking time.
  • Penne Pasta – You can use penne pasta instead of fettuccine noodles for a heartier noodle.
Fork in cajun chicken fettuccine in slow cooker.

Recipe FAQs

Can I use cajun seasoning?

You can use two teaspoons of cajun spice seasoning (such as Tony’s Chachere’s Creole Seasoning) instead of the different seasonings in this dish. Don’t add any more, for it can be on the salty side.

Why isn’t my creamy cajun pasta spicy?

Cayenne pepper loses its potency the longer it’s been on the shelf, or it can sometimes not be as spicy as other brands. You can add additional cayenne pepper after the dish is done cooking for more cajun spice.

Can I use cream cheese?

You can add a block of cream cheese to this dish instead of heavy cream. You can add it at the beginning of the cooking time or microwave it for 30 seconds before adding the dish at the end of the cooking time.

Can I add vegetables?

To make this a complete meal, add steamed broccoli or frozen peas to the pasta just before serving.

Plate of cajun chicken fettuccine.

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Fork in cajun chicken fettuccine in slow cooker.

Slow Cooker Cajun Chicken Fettuccine

4.03 from 40 votes
Prep Time: 25 minutes
Cook Time: 6 hours
Servings: 8
Tender chicken in a cajun spiced sauce cooked in the slow cooker with fettuccine noodles added.

Ingredients 
 

  • 1 cup chicken broth
  • 1/4 tsp. cayenne pepper
  • 1/2 tsp. garlic powder
  • 1/4 tsp. onion powder
  • 1/2 tsp. dried leaf oregano
  • 1/4 tsp. red pepper flakes
  • 1 1/2 tsp. paprika
  • 1 tsp. salt
  • 1/4 tsp. pepper
  • 2 lbs. boneless skinless chicken breasts
  • 1 small white onion, diced

Add at the end:

  • 1 lb. fettuccine noodles, cooked according to package directions
  • 2 cups heavy cream
  • 3/4 cup parmesan cheese, divided
  • dried parsley or oregano for garnish
  • paprika for garnish

Instructions 

  • Add the chicken broth to the slow cooker, add the cayenne, garlic powder, onion powder, oregano, red pepper flakes, paprika, salt and pepper. Stir.
  • Add the chicken breasts and flip them around in the seasoned chicken broth to get the seasonings on the chicken.
  • Sprinkle the onions over the chicken and broth.
  • Cover and cook on low for 6 hours without opening the lid during the cooking time.
  • After the cooking time is done, shred the chicken with two forks right in the slow cooker. Add the heavy cream.
  • Add the cooked and drained pasta and a ½ cup of the Parmesan cheese. Stir.
  • Sprinkle over the remaining parmesan cheese. I added a touch more paprika and also parsley flakes to the top of my pasta to make it look pretty. Cover and cook for 20 more minutes. Cooking for a bit longer helps the sauce thicken from the gluten in the pasta.
  • Serve and enjoy!

Video

Notes

  1. To make this a complete meal stir in steamed veggies into the pasta with the noodles at the end of the cooking time.
  2. You can add a block of cream cheese to this dish instead of heavy cream. You can add it at the beginning of the cooking time or microwave it for 30 seconds before adding the dish at the end of the cooking time.
  3. Cayenne pepper loses its potency the longer it’s been on the shelf or it can sometimes not be as spicy as other brands. You can add additional cayenne pepper after the dish is done cooking to taste.
  4. You can use two teaspoons of cajun spice seasoning (such as Tony’s Chachere’s Creole Seasoning) instead of the different seasonings in this dish. Don’t add any more, for it can be on the salty side.
 

Nutrition

Calories: 605kcal | Carbohydrates: 45g | Protein: 37g | Fat: 30g | Saturated Fat: 17g | Cholesterol: 210mg | Sodium: 660mg | Potassium: 679mg | Fiber: 3g | Sugar: 2g | Vitamin A: 1590IU | Vitamin C: 5mg | Calcium: 175mg | Iron: 1.9mg

Nutrition info is auto-generated. This information is an estimate; if you are on a special diet, please use your own calculations.

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Recipe Rating




212 Comments

  1. Janine says:

    Can I cook the fettuccine in the slow cooker by adding more broth?

    1. Sarah Olson says:

      Some people do add uncooked fettuccine to the slow cooker. It does cook it, but it is a chalky and mushy texture. I prefer to cook my pasta on the stove top.

  2. Anonymous says:

    Can I put the crockpot on high to speed up the cooking or does it have to strictly have to be set on low?

    1. Sarah Olson says:

      It should do fine on high.

  3. Jamie says:

    1 star
    I followed the directions and it was very bland. Nothing Cajun about it. It definitely needs double or triple the amount of spices.

    1. Sarah Olson says:

      It depends on how old your cayenne pepper is. You can always add more at the end to your tastes.

  4. Hattie says:

    5 stars
    I have made this recipe MANY times. I feel like it’s an excellent base recipe that you can customize to your liking.
    Personally I never measure spices. I just dump them in. I add extra spices to this as well. Just whatever I feel like adding. Don’t be scared to play with spices! after some time in the kitchen, you figure out how much and of what tastes good,

    I don’t measure the cheese. I just add what feels right.

    I love adding lots of onion and bell peppers. Don’t be afraid to throw your favorite veggies in this. The more veggies the better.

    I shred my chicken in my stand mixer. Just a personal preference.

  5. Tanya says:

    Is it better to use shredded parmesan cheese or grated?

    1. Sarah Olson says:

      I used grated for this recipe.

  6. Destiny says:

    5 stars
    Love this recipe!
    My family loves it as well.
    I think I’ll double the sauce next time.
    Thank You

  7. Paula says:

    Could I cook this on high for three to four hours?

    1. Sarah Olson says:

      Yes, will work fine

  8. Maylani says:

    Can you also use frozen chicken

    1. Sarah Olson says:

      Hi, I don’t give advice on frozen meat for some studies suggest it isn’t safe to cook frozen meat.

  9. Maylani says:

    Is it a meal that you can put in freezer?

    1. Sarah Olson says:

      Yes, you can put everything but the pasta, heavy cream and parmesan into the freezer. Then, thaw when ready to cook.

  10. Jordan says:

    How can I do this recipe with an instant pot?